Greetings fellow adventurers,

    Senolytics are arguably the best rejuvenation therapy currently available, and though costly, FOXO4-DRI is the most effective senolytic.
   This site is a repository for the first human experiences with this exciting new substance. And, though anecdotal, the hope is this information will prove valuable to early adopters and science1.

    I’ve been experimenting with longevity supplements/therapies for years and have seen little effect, but an exception popped up in January 2017. While experimenting with the senolytic compounds Dasatinib and Quercetin, I experienced a significant jump in my cardiovascular endurance2. My treadmill running time went from 5mins to 6mins (still nothing to write home about) and it then stabilized at about 4.5mins. If I can repeat this temporary increase with FOXO4-DRI, it would hint at efficacy. But I experienced serious side effects with Dasitinib. It felt like a bad flu. My heart raced, got chills and sweats; and when we checked my blood pressure, systolic was 186!

Experiences with FOX04-DRI have moved to a forum on Longecity here